Self-assembled FGF21 nanoparticles alleviate drug-induced acute liver injury
Acetaminophen (N-acetyl-p-aminophenol, APAP) is a common antipyretic agent and analgesic.An overdose of APAP can result in acute liver injury (ALI).Oxidative stress and inflammation are central to liver injury.N-acetylcysteine (NAC), a precursor of glutathione, is used commonly in clinical settings.However, the window of NAC treatment is limited, a